Marijuana Use NOT Associated With Increased Stroke Risk, Finds Study
According to a brand new examine revealed within the journal Neurology: Clinical Practice, the latest publicity to marijuana is just not related to an elevated danger of hospitalization attributable to acute ischemic stroke (AIS).
For the examine researchers from the University of Mississippi Medical Center examined the connection between a constructive marijuana check upon hospital admission and the probability of affected by AIS.
Researchers discovered that those that examined constructive for marijuana had a decreased danger of affected by AIS in contrast with those that examined adverse for the plant. After adjusting for confounders resembling age and weight problems, researchers discovered no vital variations in AIS danger amongst marijuana-positive sufferers.
The examine concludes by stating: “This is one of the few studies analyzing the association of recent cannabis use and acute ischemic stroke using admission urine toxicology test independent of polysubstance use. Even though our study has limitations, we did not find an independent association between recent cannabis use and the incidence of acute ischemic stroke. Further studies utilizing urine toxicology tests with larger sample size and including dosage of cannabis exposure should be done.”
The examine is titled: Association between latest cannabinoid use and acute ischemic stroke.
The examine’s full summary states:
Background: Studies which have analyzed the affiliation between hashish use and acute ischemic stroke (AIS) have offered conflicting outcomes. In this examine, we intention to find out the affiliation of latest hashish use detected via urine drug display (UDS) amongst sufferers admitted with AIS.
Methods: A retrospective observational examine was carried out utilizing the medical data database. All sufferers aged 18 years and older admitted from January 1, 2015, to December 31, 2017, who underwent urine toxicology testing on admission have been included within the evaluation. Multivariate logistic regression evaluation was carried out to investigate unbiased affiliation between latest hashish use and AIS.
Results: A complete of 9,350 sufferers have been decided to have undergone UDS throughout admission, and 18% (1,643) of this had a constructive urine hashish check. Unadjusted danger ratio confirmed a 50% lower in danger of AIS amongst hashish customers (danger ratio = 0.505, 95% confidence interval [CI] 0.425-0.600). The impact was misplaced after adjusting for age, race, ethnicity, sickle cell illness, dyslipidemia, hypertension, weight problems, diabetes mellitus, cigarette smoking, atrial fibrillation, and different cardiac situations (odds ratio 1.038, 95% CI 0.773-1.394).
Conclusion: This is without doubt one of the few research analyzing the affiliation of latest hashish use and AIS utilizing admission urine toxicology check unbiased of polysubstance use. Although our examine has limitations, we didn’t discover an unbiased affiliation between latest hashish use and the incidence of AIS. Further research utilizing urine toxicology assessments with bigger pattern measurement and together with dosage of hashish publicity must be performed.