CAMBRIDGE, Mass.–(BUSINESS WIRE)–Goldfinch Bio, a medical stage biotechnology firm targeted on discovering and creating precision medicines for the remedy of kidney ailments, at present introduced that it has been named by Fierce Biotech as one of 2020’s Fierce 15 biotechnology corporations, designating it as one of probably the most promising personal biotechnology corporations within the business.
The 2020 Fierce 15 comes at a time when the world is targeted on a pandemic, however even as coronavirus stays a menace, sufferers with most cancers, uncommon ailments and different problems nonetheless want remedy, FierceBiotech Senior Editor Ben Adams mentioned, “This year, we’ve chosen from a diverse range of those fighting COVID, as well as those fighting longer term plagues against our biology.”
Goldfinch Bio is a medical stage biotechnology firm which is driving innovation in kidney genetics and biology to pioneer a brand new remedy paradigm for folks recognized with kidney ailments. Goldfinch Bio’s strategy is rooted in its proprietary precision medication kidney platform, which contains the Company’s Kidney Genome Atlas (KGA), human kidney organoid and podocyte fashions, and small molecule chemistry. Goldfinch Bio’s lead precision medication candidate is GFB-887, a first-in-class small molecule inhibitor concentrating on Transient Receptor Potential Canonical Channel 5 (TRPC5), which is presently in an ongoing Phase 2 medical trial for the remedy of sufferers with focal segmental glomerulosclerosis (FSGS) and diabetic nephropathy (DN)1. The Company can also be creating GFB-024, a peripherally-restricted cannabinoid receptor 1 (CB1) inverse agonist monoclonal antibody, for the remedy of uncommon and metabolic kidney ailments and expects to submit an investigational new drug (IND) software in 2021.
“We are thrilled to be distinguished by Fierce Biotech among the industry’s leading innovators, reflecting the potential of our precision medicine platform to revolutionize the treatment paradigm for people living with severe and debilitating kidney diseases,” mentioned Anthony Johnson, M.D., President and Chief Executive Officer of Goldfinch Bio. “Kidney disease is a major global epidemic that affects approximately 10%, or 760 million people worldwide.2 There has been a disproportionately low level of investment and innovation in the kidney disease space compared to other therapeutic areas, despite the significant financial and emotional burden to those diagnosed and to the healthcare system at large. We are committed to delivering novel medicines to defined patient subsets, with the goal of preserving kidney function, eliminating the need for dialysis, and improve patients’ quality of life.”
The Fierce 15 celebrates the spirit of being “fierce” – championing innovation and creativity, even within the face of intense competitors. This is Fierce Biotech’s 18th annual Fierce 15 choice.
An internationally acknowledged day by day report reaching a community of over 285,000 biotech and pharma business professionals, Fierce Biotech gives subscribers with an authoritative evaluation of the day’s prime tales. Every yr Fierce Biotech evaluates a whole bunch of personal corporations from world wide for its annual Fierce 15 record, which relies on a range of elements such as the power of its expertise, partnerships, enterprise backers and a aggressive market place.
About Fierce Biotech
Fierce Biotech is the biotech business’s day by day monitor, an e mail publication and internet useful resource offering the most recent biotech information, articles, and sources associated to medical trials, drug discovery, FDA approval, FDA regulation, patent information, pharma information, biotech firm information and extra. More than 150,000 prime biotech professionals depend on Fierce Biotech for an insider briefing on the day’s prime tales. Signup is free at www.fiercebiotech.com/signup.
About Goldfinch Bio
Goldfinch Bio, Inc. is a medical stage biotechnology firm that leverages a genomics-based, precision medication strategy to discovering and creating kidney illness therapies. Its Kidney Genome Atlas (KGA™) is a proprietary biology platform that drives candidate discovery, biomarker growth and affected person choice. The Company’s lead candidate, GFB-887, is a TRPC5 ion channel inhibitor, in Phase 2 growth for the remedy of kidney ailments. Goldfinch Bio can also be creating GFB-024, a peripherally-restricted cannabinoid receptor 1 (CB1) inverse agonist monoclonal antibody, for the remedy of uncommon and metabolic kidney ailments and expects to submit an investigational new drug (IND) software in 2021. Goldfinch Bio, headquartered in Cambridge, Massachusetts, was launched in 2016 by Third Rock Ventures and has a longtime strategic collaboration with Gilead Sciences, Inc. For extra details about Goldfinch Bio, go to www.goldfinchbio.com.
1 Patients recognized with remedy resistant minimal change illness, which is taken into account a subset of FSGS, can even be allowed into the Phase 2 medical.
2Kittiskulnam, et al,. Semin Nephrol. Author manuscript; accessible in PMC 2017 Jul 1. Published in last edited type as: Semin Nephrol. 2016 Jul; 36(4): 305–318. doi: 10.1016/j.semnephrol.2016.05.007 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967875/