Cannabis sativa has lengthy been used for medicinal functions. To enhance security and efficacy, compounds from C. sativa have been purified or synthesized and named underneath an umbrella group as cannabinoids. Currently, a number of cannabinoids could also be prescribed in Canada for quite a lot of indications equivalent to nausea and ache.
More not too long ago, an rising variety of experiences recommend different salutary results related to endogenous cannabinoid signaling together with cardioprotection. The therapeutic potential of cannabinoids is subsequently prolonged; nevertheless, proof is restricted and mechanisms stay unclear. In addition, the usage of cannabinoids clinically has been hindered as a consequence of pronounced psychoactive negative effects.
This evaluation supplies an outline on the endocannabinoid system, together with identified physiological roles, and circumstances in which cannabinoid receptor signaling has been implicated.