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Cannabis could possibly be the solely therapy essential to alleviate the signs related to fibromyalgia syndrome.

What is Fibromyalgia Syndrome (FMS)?

That definition or prognosis varies relying on the sort of practitioner you ask and their perception of what this situation really is. The motive for that is the incontrovertible fact that there isn’t any “golden standard” for diagnosing FMS. The basic acutely aware is that FMS is the presence of continual, widespread musculoskeletal ache, that could be accompanied with migraines, insomnia, irritable bowel syndrome (IBS), reminiscence issues, temper swings, and fatigue, simply to call a couple of. Recent analysis has proven that people identified with FMS have irregular ache notion processing. This situation primarily impacts girls and is often identified between the ages of 20-40 +/-.  According to the Centers for Disease Control and Prevention (CDC), roughly four million adults in the US are affected by fibromyalgia (CDC, 2017).

If you’re at present experiencing signs that fall inside the prognosis of FMS, you understand your self, that your personal signs may fluctuate from everyday. The most irritating factor about it although, is that many sufferers by no means discover substantial aid from these signs regardless of the use of a number of prescribed medicines. Others searching for therapy could even be undiagnosed or misdiagnosed. At Nature’s Way Medicine, we offer complete assessments for sufferers all for treating FMS, or different medical situations via the use of medical marijuana.

New data associated to FMS and the endocannabinoid system

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The Endocannabinoid System

The endocannabinoid system is a just lately found system inside the human physique. In the early 1990s, a number of researchers found this method (Alger, 2103), together with the receptors which can be situated in the central nervous system (CB1), in the peripheral nervous system and organs associated to immunity (CB2). With the discovery of these receptors got here the data of naturally occurring neurotransmitters referred to as endocannabinoids (endo- inside or inside).  Without stepping into the chemistry of the system, these receptors reply to the cannabinoids made by the physique in addition to these present in Cannabis. So, one may ask themselves… Why do we have now these receptors in our physique, if we weren’t meant to make use of Cannabis to deal with illnesses?

Endocannabinoid Deficiency and Fibromyalgia

Today, extra details about FMS and its doable connection to the endocannabinoid system (ECS) is out there, and the analysis is exhibiting a possible hyperlink to the trigger of the signs being related to a deficiency on this system. The concept is that the ECS has the potential to control and steadiness the methods inside the physique. It is believed that in sure situations, whether or not congenital or acquired, the perform of the ECS turns into poor and causes numerous syndromes. Fibromyalgia could also be one of these syndromes; but, there may be nonetheless inconclusive proof on this matter (Habib & Artul, 2018).

If we have a look at the principal complaints related to FMS, we discover vital proof of the efficacy of Cannabis to deal with these particular person signs.

  • Chronic Pain (CP) — The ECS is now identified to be one of the key methods that regulate ache sensation, with distinct actions in any respect levels of ache processing pathways (Woodhams et al., 2015). So, if the ache regulation inside the ECS just isn’t working accurately, this might, in flip, trigger the ache related to FMS. A examine revealed in The Journal of Pain acknowledged that their findings counsel that many CP sufferers are basically substituting medical Cannabis for opioids and different medicines for CP therapy and discovering the advantages of Cannabis to be higher than these different lessons of medicines (Boehnke et al., 2016).
  • Insomnia — Preliminary analysis into Cannabis and insomnia means that CBD could have therapeutic potential for the therapy of insomnia, whereas THC could lower sleep latency (the time it takes to go to sleep). A latest examine used a preferred app to find out the efficacy of Cannabis when used to alleviate insomnia. They discovered that the consumption of medical Cannabis flower amongst their members was related to vital enhancements in perceived insomnia. There was, nevertheless, a distinction in the effectiveness and unwanted effects, relying on the product they used and the way it was administered (Vigil et al., 2018).
  • Migraines — Traditionally, migraines have been handled with calcium channel blockers, beta-blockers, and topiramate in a prophylactic method. They could cause some undesirable unwanted effects although. Research has proven that Cannabis seems to change the nociceptive (ache from nerve cells) processes in the mind and may perform by way of serotonergic (nerve ending stimulated by serotonin) and different pathways concerned in migraines. When inhaled, it’s quickly activated and skips the digestive system. This is a big profit as a result of intestinal absorption is markedly decreased throughout a migraine and that many migraine sufferers expertise nausea and vomiting as a typical symptom. It ought to be famous that Cannabis is a extremely efficient antiemetic as nicely (Chirchiglia et al., 2017).

One frequent drawback that we see right this moment with validating the use of Cannabis is that it’s nonetheless a Schedule 1 drug in the United States. Despite the reality that each one however 19 states have legalized the use of medical Cannabis or Cannabis use for leisure use, it’s nonetheless unlawful to own, use and develop Cannabis in the US. This archaic regulation impedes the progress of analysis to would allow extra research to find out the full medicinal advantages of Cannabis.

Nature’s Way Medicine gives medical marijuana playing cards for sufferers trying to relieve signs of FMS and different medical situations in an efficient method. Our physicians conduct thorough medical marijuana assessments to make sure our sufferers are conscious of all dangers and advantages of treating their medical situation with hashish. To schedule a session, please contact us at 855-420-3627. For questions or inquiries, you might fill out our contact kind.

References

Alger, B. E. (2013, November). Getting excessive on the endocannabinoid system. In Cerebrum: the Dana discussion board on mind science (Vol. 2013). Dana Foundation. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997295/.

Boehnke, Okay. F., Litinas, E., & Clauw, D. J. (2016). Medical Cannabis use is related to decreased opiate treatment use in a retrospective cross-sectional survey of sufferers with continual ache. The Journal of Pain, 17(6), 739-744. doi.org/10.1016/j.jpain.2016.03.002

Centers for Disease Control and Prevention (CDC). National Center for Chronic Disease Prevention and Health Promotion , Division of Population Health. (2017). Fibromyalgia. Retrieved from https://www.cdc.gov/arthritis/basics/fibromyalgia.htm

Chirchiglia, D., Della Torre, A., & Chirchiglia, P. (2017). Focus on the endogenous cannabinoid system in migraine. EMJ Neurology, 5(1), 88-91. Retrieved from https://www.researchgate.net/profile/Domenico_Chirchiglia/publication/318878241_Focus_on_the_endogenous_cannabinoid_system_in_migraine/links/598c2467458515c333a69f4c/Focus-on-the-endogenous-cannabinoid-system-in-migraine.pdf

Habib, G., & Artul, S. (2018). Medical Cannabis for the therapy of fibromyalgia. JCR: Journal of Clinical Rheumatology, 24(5), 255–258. doi:10.1097/RHU.0000000000000702

Vigil, J.M., Stith, S.S., Diviant, J.P., Brockelman, F., Keeling, Okay., & Hall, B. (2018). Effectiveness of uncooked, pure medical Cannabis flower for treating insomnia below naturalistic situations. Medicines, 5(3), 75. doi.org/10.3390/medicines5030075

Woodhams, S. G., Sagar, D. R., Burston, J. J., & Chapman, V. (2015). The position of the endocannabinoid system in ache. In Pain management (pp. 119-143). Springer, Berlin, Heidelberg. doi.org/10.1007/978-3-662-46450-2_7



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